ABSTRACT
Histopathological changes were observed in liver, kidney and muscles of normal, protein-malnourished, diabetic as well as both protein-malnourished and diabetic albino rats when exposed to a mixture of monocrotophos, hexachlorocyclohexane and endosulfan at varying intervals. The examination revealed hepatotoxic, nephrotoxic and muscular necrotic effects in pesticides exposed rats. Toxicity was aggravated in protein-malnourished and diabetic animals and more so, if the animals were both diabetic and protein-malnourished.
Subject(s)
Animals , Diabetes Mellitus/pathology , Endosulfan/pharmacology , Female , Kidney/drug effects , Hexachlorocyclohexane/pharmacology , Liver/drug effects , Male , Malnutrition/pathology , Monocrotophos/pharmacology , Muscles/drug effects , Pesticides/pharmacology , Rats , Rats, WistarABSTRACT
The quality of extruded faba bean (EFB) (Vicia faba L.) as a protein supplement in cereals diet was evaluated. Growth rate and protein efficiency ratio was better in 20% EFB blended dietary group of rats than those fed either on cereals alone or at 40% EFB supplementation. Subsequent studies on digestibility co-efficient, biological value, net protein utilization and net protein ratio also confirmed biological utilization of EFB proteins in a better way at low level (20%).